Eight male, nonsmoking volunteers between the ages of 18 and 50 years (mean age, 40.6 years) were recruited for the study. The subjects took a daily dose of 10 mg of lutein, in the form of lutein diesters derived from marigolds, for a period of 12 weeks. The supplementation induced an increase in mean plasma lutein by a factor of 5 and a linear 4-week increase in relative macular pigment density of 5.3%. Lutein supplementation can significantly improve blood lutein and macular pigment density, thus improving the symptoms of macular degeneration.
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